An English actress of film, stage, and television
She made her film debut in K. M. Peyton's A Pattern of Roses before winning her first leading role as the titular character in Lady Jane. She is known for her roles in films such as A Room with a View, Fight Club, and the Harry Potter series, as well as for frequently collaborating with director Tim Burton, her domestic partner since 2001. Bonham Carter is a two-time Academy Award nominee for her performances in The Wings of the Dove and The King's Speech; her portrayal of Queen Elizabeth in the latter film garnering her a BAFTA Award in 2011.
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Include Duchenne is an exciting new education project funded by Action Duchenne, the National Lottery through the Big Lottery Fund and Children in Need. It aims to give young people with Duchenne better educational opportunities and experiences and is based on current research.
Through its ‘Decipha’ Programme learners will be able to:
The project will form part of a research project with the Centre for Child Research at the University of Wales, Swansea.
Duchenne muscular dystrophy (Duchenne) is a severe recessive X-linked form of muscular dystrophy characterized by rapid progression of muscle degeneration, eventually leading to paralysis and early death. This affects one in 3500 males, making it the most prevalent of muscular dystrophies. In general, only males are afflicted, though females can be carriers. The disorder is caused by a mutation in the dystrophin gene, located in humans on the X chromosome. The Dystrophin gene codes for the protein dystrophin, an important structural component within muscle tissue. Dystrophin provides structural stability to the dystroglycan complex (DGC), located on the cell membrane.
About Action Duchenne
Action Duchenne was established to find a cure or more effective medicines to treat Duchenne Muscular Dystrophy.
Since 2001 we have funded key research projects and supported clinical trials that are making real progress towards our key aim.
Our Research programme is now producing real results in terms of clinical trialling new drugs to treat Duchenne Muscular Dystrophy.
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